52) L. Palanikumar, E. Choi, J. Y. Oh, S. A. Park, H. Choi, J.-H. Ryu* "High encapsulation stability of mesoporous silica nanoparticles with non-covalent polymer gatekeepers for enhanced in vivo cancer therapeutics" 2018, submitted

51) H. Park, Y. Choi, M. T. Jeena, E. Ahn, Y. Cho, M.-G. Kang, C. G. Lee, T.-H. Kwon, H.-W. Rhee, J.-H. Ryu, B.-S. Kim* "Reduction-Triggered Self-Cross-Linked Hyperbranched Polyglycerol Nanogels for Intracellular Delivery of Drugs and Proteins" Macromol. Biosci. 2018, in press

50) S. Kim, L. Palanikumar, H. Choi, M. T. Jeena, C. Kim*, J.-H. Ryu* "Intra-Mitochondrial Biomineralization for Inducing Apoptosis of Cancer Cells" Chem. Sci. 2018, 9, 2474-2479


49) Yang, S.; Palanikumar, L.: Jeong, S.; Kim, K.; Lee, J.; Kim, C.;* Ryu, J.-H.;* Park, M.-H.* "Synergistic Effect of Photothermal Therapy and Photochemotherapy using Camptothecin-conjugated Gold Nanorods" Part. Part. Syst. Char. 2018, 35, 1700307

제목 없음


48) Song, J.; Palanikumar, L.; Choi, Y.; Kim, I.; Heo, T.-y.; Ahn, E.; Choi,  S.-H.; Lee, E.; Shibasaki, Y.; Ryu, J.-H.; Kim, B.-S.*  "The Power of the Ring: pH-Responsive Hydrophobic Epoxide Monomer for Superior Micelle Stability" Polym. Chem. 2017, 8, 7119 (December 14, 2017)

47) Thomas, A. P.; Palanikumar, L.; Jeena, M.T.; Kim, K.; Ryu, J.-H.* "Cancer Mitochondria-Targeted Photodynamic Therapy with Supramolecular Assembly of HA and Near IR Cyanine Dye" Chem. Sci. 20178, 8351 (December 01, 2017)


46) Jeena, M. T.; Palanikumar, L.; Go, E. M.; Kim, I.; Kang, M. G.; Lee, S.; Park, S.; Choi, H.; Kim, C.; Jin, S.-M.; Bae, S. C.; Rhee, H.-W; Lee, E.; Kwak, S. K.; Ryu, J.-H.* "Mitochondria localization induced self-assembly of peptide amphiphiles for cellular dysfunction" Nat. Commun. 2017, 8, 26 (June, 21, 2017) (News: KBS, Arirang TV)

제목 없음

45) Palanikumar, L.; Jeena, M. T.; Kim, K.; Oh, J. Y.; Kim, C.; Park, M.-H.; Ryu, J.-H.* "Spatiotemporally and Sequentially-Controlled Drug Release from Polymer Gatekeeper-Hollow silica Nanoparticles" Sci. Rep. , 2017, 7, 46540 (April, 24, 2017)


44) Cho, A; La, Y; Jeoung, S; Moon, H.R; Ryu, J.-H; Shin, T; Kim, K.T.* "Mix-and-Match Assembly of Block copolymer Blends in Solution" Macromolecules, 2017(April, 4, 2017)


43) Kim, K.; Choi, H.; Choi, E.; Ryu, J.-H.*  “Encapsulation stability of the polymeric assembly (고분자 조립체의 Encapsulation 안정성) "고분자 과학과 기술 제27권 제2호, 2016.4, 142-147. Polymer Society of Korea (mini-review, written in Korean)

42) Kim, K.; Jo, M.C.; Jeong, S.;  Palanikumar, L.; Rotello, V. M.; Ryu, J.-H.*; Park, M.-H.*  "Externally controlled drug release using a gold nanorod contained composite membrane" Nanoscale , 2016, 8, 11949-11955. (May, 17, 2016)


41) Choi, H.; Jeena, M.T.; Palanikumar, L.; Jeong, Y.; Park, S.; Lee, E.*; Ryu, J.-H.* "HA-incorporated nanostructure of peptide-drug amphiphile for targeted anticancer drug delivery" Chem. Commun. 201652, 5637-5640. (Mar, 22. 2016)


40) Jeena, M. T.; Bok, T; Kim, S. H.; Park, S.; Kim, J.-U.; Park, S.*; Ryu, J.-H.*  “Siloxane incorporated copolymer as an in situ cross-linkable binder for high performance silicon anode in Li-ion battery" Nanoscale 2016, 8,9245-9253. (Mar. 30, 2016)

제목 없음1


39) Palanikumar, L.; Kim, H.: Oh, J. Y.; Thomas, A. P.; Choi, E. S.; Jeena, M. T.; Joo, S. H.; Ryu, J.-H.*  “Noncovalent Surface Locking of Mesoporous Silica Nanoparticles for Exceptionally High Hydrophobic Drug Loading and Enhanced Colloidal Stability" Biomacromolecules 201516, 2701-2714. (Sep. 14, 2015)


38) Yang, S. H.*; Choi, J.; Palanikumar, L.; Choi, E. S.; Lee, J.; Kim, J.; Choi, I. S.*; Ryu, J.-H.*  “ Cytocompatible In Situ Cross-Linking of Degradable LbL Films Based on Thiol-Exchange Reaction  Chem. Sci. 2015, 6, 4698-4703.(Aug. 01, 2015)


37) Lee, C.*; Park, H.-K.; Jeong, H; Lim, J.;Lee, A.-J.; Cheon, K. Y.; Kim, C.-S.; Thomas, A. P.; Bae, B.; Kim, N. D.; Kim, S. H.; Suh, P.-G.; Ryu, J.-H.*; Kang, B. H.*  “ Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1 J. Am. Chem. Soc. 2015, 137, 4358-4367. (Apr. 8, 2015)


36) Palanikumar, L.; Choi, E. S.; Cheon, J. Y.; Joo, S. H.*; Ryu, J.-H.*  “Noncovalent Polymer-Gatekeeper in Mesoporous Silica Nanoparticles as a Targeted Drug Delivery Platform" Adv. Funct. Mater. 2015, 25, 957-965.(Feb. 11, 2015)



35) Jeena, M. T.; Lee, J.-I; Kim, S. H.; Kim, C.; Kim, J.-Y.; Park, S.*; Ryu, J.-H.*  “Multifunctional Molecular Design as an Efficient Polymeric Binder for Silicon Anodes in Lithium-Ion Batteries ACS Appl. Mater.  Interfaces 2014 6, 18001–18007. (Oct. 22, 2014)



34) Kim, K.; Bae, B.; Kang, Y. J.; Nam, J.-M.; Kang, S.; Ryu, J.-H.*  “ Natural Polypeptide-Based Supramolecular Nanogels for Stable Noncovalent Encapsulation Biomacromolecules 2013, 14, 3515-3522.  (Oct. 14, 2013)


33) Li, L.; Ryu, J.-H.; Thayumanavan, S.  “ Effect of Hofmeister Ions on the Size and Encapsulation Stability of Polymer Nanogels Langmuir 2013, 29, 50-55. (Jan. 8, 2013)


Prior to joining UNIST

32) Kim, H.-J. +; Liu, F. +; Ryu, J.-H. +; Ungar, G.; Lee, J.-K.; Zin, W.-C.; Lee, M. “Self-Organization of Bent Rod Molecules into Hexagonally-Ordered Vesicular Columns J. Am. Chem. Soc. 2012, 134, 13871-13880. (+These authors contributed equally to this work)

31) Choi, I.; Park, I.-S.; Ryu, J.-H.; Lee, M. “Control of Peptide Assembly Through Directional InteractionsChem. Commun. 2012, 48, 8481-8483. (Selected to inside Cover). 

30) Gonzalez, D.+; Ryu, J.-H.+; Chacko, R. T.; J. Zhuang; Thayumanavan, S. “Concurrent Binding and Delivery of Proteins and Lipophilic Small Molecules Using Polymeric NanogelsJ. Am. Chem. Soc. 2012, 134, 6964-6967. (+ These authors contributed equally to this work)

29) Ryu, J.-H.; Bickerton, S.; J. Zhuang; Thayumanavan, S. “Ligand-Decorated Nanogels: Fast One-Pot Synthesis and Cellular TargetingBiomaromolecules 2012, 13, 1515-1522

28) Ryu, J.-H.; Chacko, R. T.;  Jiwpanich, S.; Bickerton, S.; Babu, R. P.; Thayumanavan, S.  “Self-crosslinked polymer nanogels: a novel platform for intracellular delivery vehiclesJ. Am. Chem. Soc. 2010, 132, 17227-17235.

27) Jiwpanich, S.; Ryu, J.-H.; Bickerton, S.; Thayumanavan, S. “Noncovalent Encapsulation Stabilities in Supramolecular NanoassembliesJ. Am. Chem. Soc. 2010, 132, 10683-10685

26) Ryu, J.-H.; Jiwpanich, S.; Chacko, R.; Bickerton, S.; Thayumanavan, S. “Surface-Functionalizable Polymer Nanogels with Facile Hydrophobic Guest Encapsulation CapabilitiesJ. Am. Chem. Soc. 2010, 132, 8246-8247.

25) Ryu, J-H.; Roy, R.; Ventura, J. Thayumanavan, S. Redox-Sensitive Disassembly of Amphiphilic Copolymer Based MicellesLangmuir 2010, 26, 7086-7092. 

24) Ryu, J.-H.; Park, S.; Kim, B.; Klaikherd, A.; Russell, T. P.; Thayumanavan, S. “Highly Ordered Gold Nanotubes Using Thiols at a Cleavable Block Copolymer interfaceJ. Am. Chem. Soc. 2009, 131, 9870-9871.

22) Ryu, J.-H.; Lee, M. “Liquid Crystalline Assembly of Rod-Coil MoleculesStructure and Bonding 2008, 128, 63-98. (Review Article)

21) Ryu, J.-H.; Hong, D.-J.; Lee, M. “Aqueous Self-Assembly of Aromatic Rod Building BlocksChem. Commun.2008, 1043-1054. (Feature Article)

20) Ryu, J.-H.; Tang, L.; Lee, E.; Kim, H.-J.; Lee, M. “Supramolecular Helical Columns from Self-Assembly of Chiral Rods Chem. Eur. J. 2008, 14, 871-881

19) Huang, Z.; Ryu, J.-H.; Lee, E.; Lee, M. Tunable Columnar Organization by Twisted Stacking of End-Capped Aromatic Rods Chem. Mater. 2007, 19, 6569-6574.

18) Lim, Y.-b.; Park, S.; Lee, E.; Ryu, J.-H.; Yoon, Y.-R.; Kim, T.-H.; Lee, M. Tunable Bacterial Agglutination and Motility Inhibition by Self-Assembled Glyco-Nanoribbons Chem. Asian J. 2007, 2, 1363-1369. (Cover Picture)

17) Lee, E.; Ryu, J.-H.; Park, M.-H.; Lee, M.; Han, K.-H.; Chung, Y.-W.; Cho, B.-K. “Observation of an unprecedented body centered cubic micellar mesophase from rod–coil moleculesChem. Commun. 2007, 2920-2922.

16) Ryu, J.-H.; Lee, E.; Lim, Y.-b.; Lee, M. Carbohydrate-Coated Supramolecular Structures: Transformation of Nanofibers into Spherical Micelles Triggered by Guest Encapsulation J. Am. Chem. Soc. 2007, 129, 4808-4814.

15) Lim, Y.-b.; Park, S.; Lee, E.; Jeong, H.; Ryu, J.-H.; Lee, M.S.; Lee, M. “Glycoconjugate Nanoribbons from Self-Assembly of Carbohydrate-Peptide Block Molecules for Controllable Bacterial Cell Cluster FormationBiomaromolecules 2007, 8, 1404-1408.

14) Park, M.-H.; Ryu, J.-H.; Han, K.-H.; Chung, Y.-W.; Cho, B.-K.; Lee, M. Chain Architecture Dependent 3-Dimensional Supramolecular Assembly of Rod-Coil Molecules with Conjugated Hexa-p-phenylene RodMacromol. Rapid. Commun. 2006, 27, 1684-1688.

13) Ryu, J.-H.; Cho, B.-K.; Lee, M. Supramolecular Assembly of Rigid-Flexible Block Molecules into Organized Nanostructures Bull. Kor. Chem. Soc. 2006, 27, 1270-1282. (Review Article)

12) Ryu, J.-H.; Kim, H.-J.; Huang, Z.; Lee, E.; Lee, M. Self-Assembling Molecular Dumbbell: From Nanohelices to Nanocapsules Triggered by Guest Intercalation  Angew. Chem. Int. Ed. 2006, 45, 5304-5307.

11) Jin, Y.J.; Bae, J.; Ryu, J.-H.; Lee, M. Ordered Nanostructures from Self-Assembly of Reactive Coil-Rod-Coil Molecule Angew. Chem. lnt. Ed. 2006, 45, 650-653.

10) Ryu, J.-H.; Lee, M. Transformation of Isotropic Fluid to Nematic Gel Triggered by Dynamic Bridging of Supramolecular Nanocylinders.J. Am. Chem. Soc. 2005, 127, 14170-14171.

9) Ryu, J.-H.; Jang, C.-J.; Yoo Y.-S.; Lim, S.-G.; Lee, M. “Supramolecular Reactor in Aqueous Environment: Aromatic Cross Suzuki Coupling Reaction at Room TemperatureJ. Org. Chem. 2005, 70, 8956-8962.

8) Kim, B.-S.; Yang, W.-Y.; Ryu, J.-H.; Yoo, Y.-S.; Lee, M. Carbohydrate-Coated Nanocapsules from Amphiphilic Rod-Coil Molecule: Binding to Bacterial Type 1 PiliChem Commun. 2005, 2035-2037.

7) Ryu, J.-H.; Bae, J.; Lee, M. “Helical Organization of m-Linked Rigid Polymers with Pendant Flexible DendronsMacromolecules 2005, 38, 2050-2052.

6) Ryu, J.-H.; Oh, N.-K.; Lee, M. Tubular Assembly of Amphiphilic Rigid Macrocycle with Flexible DendronsChem. Comm. 2005, 1770-1772.

5) Jang, C.-J.; Ryu, J.-H.; Lee, J.-D.; Shon, D.; Lee, M. “Synthesis and Supramolecular Nanostructure of Amphiphilic Rigid Aromatic-Flexible Dendritic Block MoleculesChem. Mater. 2004, 16, 4226-4231.

4) Lee, M; Jang, C.-J.; Ryu, J.-H.Supramolecular Reactor from Self-Assembly of Rod-Coil Molecule in Aqueous EnvironmentJ. Am. Chem. Soc. 2004, 126, 8082-8083.

3) Oh, N.-K.; Zin, W.-C.; Im, J.-H.; Ryu, J.-H.; Lee, M. Organization of Branched Rod-Coil Molecule into a 3-D Tetragonally Perforated Lamellar StructureChem. Commun. 2004, 1092-1093.

2) Ryu, J.-H.; Oh, N.-K.; Zin, W.-C.; Lee, M. Self-Assembly of Rod-Coil Molecules into Molecular Length-Dependent OrganizationJ. Am. Chem. Soc. 2004, 126, 3551-3558.

1) Cho, B.-K.; Ryu, J.-H.; Zin, W.-C.; Lee, M. “Synthesis of Liquid Crystalline Rod-Coil Dimers based on Poly(propylene oxide) Coil” Polym. Bull. 2000, 44, 393-400.