October, 2018. Jun Yong & Palani's paper were published in Nature communication. Congratulation!
Nanomedicine for Cancer TherapyAdvances in water-insoluble drug delivery systems are limited by selective delivery, loading capacity, and colloidal and encapsulation stability.
Mitochondria Targeting DrugThe mitochondrial pool of Hsp90 and its mitochondrial paralogue, TRAP1, suppresses cell death and reprograms energy metabolism in cancer cells; therefore, Hsp90 and TRAP1 have been suggested as target proteins for anticancer drug development.
Mitochondria localization induced self-assembly of peptide amphiphilesMito-FF preferentially accumulates inside mitochondria and reaches the critical aggregation concentration to form a fibrous nanostructure. The Mito-FF fibrils induce mitochondrial dysfunction via membrane disruption to cause apoptosis.
Cloaking nanoparticles shield for targeted drug deliveryTargeted drug delivery using nanoparticles can minimize the side effects of conventional pharmaceutical agents and enhance their efficacy. So we present a targeting strategy for nanoparticles incorporated with a supramolecularly pre-coated recombinant fusion protein.
Ryu Group at UNIST : Supramolecular Chemistry From Molecules To Materials
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July, 2018. Huyeon's paper got accepted in ACS omega. Congratulation!
June, 2018. Palani's paper was published in Biomacromolecules. Congratulation!
March, 2018. Palani's paper was published in ACS Biomater. Sci. Eng. Congratulation!
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